Heterociklična jedinjenja su ciklična jedinjenja koja pored ugljenika sadrže u strukturi prstena jedan ili više atoma nekih drugih elemenata-. Start studying Heterociklična jedinjenja (Petočlana). Learn vocabulary, terms, and more with flashcards, games, and other study tools. izvor: Wikipedia. Stranice: Poglavlja: Heterociklična Jedinjenja (2 prstena), Heterociklična Jedinjenja (3 prstena), Heterociklična Jedinjenja (4 ili više.

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geterociklicna N-Methylpyridone is used in the production of compounds that are used to produce images [22]. A randomized, placebo-controlled study, Movement Disord.

The review is divided in three parts.


Wang, Microwave-assisted solvent-free synthesis of substituted 2-quinolones, Tetrahedron 63 The obtained enaminones, without purification, react with different methylene nitriles at [degrees]C for 5 min in 2-propanol and in the presence of a catalytic amount of piperidine base.

Petrovic, Primena mikrotalasne tehnike u organskoj hemiji i organskoj hemijskoj tehnologiji, Hem. Delgado, A novel approach to the indoloquinoline alkaloids cryptotackieine and cryptosanguinolentine by application of cyclization of ovinyl-substituted arylheterocumulenes, Tetrahedron 57 Sestoclana heterociklicna jedinjenja koja sadrze azot npr.

Swanson, Synthesis and Biological activity of kappa opioid receptor agonists. Copy the Heterocikljcna URL. Synthesis of 5-phenylazo-4,6-dimethylcyanopyridones and 5-phenylazo-4,6-diphenylcyanopyridone are shown in Figure 7.

Similarly, the synthesis of the 5-phenylazohydroxymethylcyanopyridones starting from [beta]-phenylazo ketoesters under the same conditions was performed Figure 7, Table 1, entries Listen Larger documents may require additional load time.


Almqvist, Pilicides–small molecules targeting bacterial virulence, Org. Scola, Heteroicklicna of Isoquinoline Alkaloids. Agrawal, A simple and convient synthesis of 4,6-disubstituted 3-cyanopyridin-2 1H -ones under solvent-free microwave conditions, Indian J.

US US This pyridone can also be obtained using conventional synthesis with potassium hydroxide as a catalyst [27,53]. Krstic, Condensation of 1,3-diketones with cyanoacetamide: The presence of [R.

Reactions were performed in 1,2-dichloroethane DCE at [degrees]C for s [80]. Unlike conventional conditions high temperature, polar organic solventsthe newer approach, enzymatically catalyzed synthesis of 2-pyridones, carried under mild reaction conditions, is characterized by high regio- and stereo-selectivity, high purity and final yield of heterociklocna obtained products [38,39].

In comparison to conventional synthesis, microwave reactor synthesis shows that the reaction is 5 or more times faster using microwave technique. The conventional way of performing organic synthesis involves heating by external heat sources e.

Heterociklično jedinjenje

Petrovic, Milrinon-svojstva i sinteza, Hem. An example of type condensation of 3-cyanopyridones is shown in Figure 3 [28]. Mohan, Bismuth Compounds in Organic Synthesis. MarkovicDanijela V.

Heterociklično jedinjenje — Википедија, слободна енциклопедија

Due to increased product yields and purity, lower waste and sometimes solvent free conditions, microwave assisted syntheses are among the methods that respect the principles of the “green chemistry”. Grossmann, Heherociklicna of known and potential antioxidants on animal models of pathological processes diabetes, gastric lesions, allergic bronchospasmExp. El-Kashef, Synthesis of 4-alkyl aryl arylcyano-2 1H -pyridinones and their 2-imino isosteres as nonsteroidal cardiotonic agents, Farmaco 54 Microwave synthesis is among methods that respect the principles of the so-called “green chemistry” which is one more reason for performing this type of synthesis [50].


At the end of the review several examples of microwave synthesis of other 2-pyridone based compounds ring fused W-substituted 2-pyridones are given.

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In the first part, microwave synthesis of 2-pyridones according to the type of condensation is discussed. Thus conducted synthetic route yield pyridone ring from fragments containing different numbers of carbon atoms. Agarwal, Microwave prompted multigram synthesis, structural determination, and photo-antiproliferative activity of fluorinated 4-hydroxyquinolinones, Bioorg. A case study, Tetrahedron 58 In a similar way, 2-quinolones can be obtained from o-aminoarylketones and acetoacetic ester using microwave synthesis min at [degrees]C in the presence of a catalyst Ce[Cl.

Jovancic, Synthesis, properties and colour assessment of some new 5- 3- and 4-substituted phenylazo -4,6-dimethylcyanopyridones, J. The method is applicable not only to aromatic aldehydes with electron-donor and electron-acceptor groups, but also to heterocyclic and aliphatic aldehydes.